4-(Trifluoromethyl)-2-pyridone (CAS number 50650-59-4), also known as 2-hydroxy-4-(trifluoromethyl)pyridine, bears the structure of 2-pyridone with an electron deficient trifluoromethyl group at 4-position of the pyridyl ring. 2-Pyridones are well-known organic compounds to form dimers via hydrogen bonding. 4-(Trifluoromethyl)-2-pyridone is a classic example that exists as tautomers, hence also known as 2-hydroxy-4-(trifluoromethyl)pyridine.
The trifluoromethyl group is considered to be one of the most powerful electron withdrawing groups yet with a significant electronegativity between that of fluorine and chlorine. Pyridone is a well known inhibitor for serotonin uptake used to treat major depressive disorder.