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5-(三氟甲氧基) 靛红

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产品名称: 5-(三氟甲氧基) 靛红
产品型号: 169037-23-4
产品展商: Ossila

简单介绍


5-(三氟甲氧基) 靛红  的详细介绍

5-(Trifluoromethoxy)isatin (CAS number 169037-23-4), a derivative of indole, has two carbonyls at 2,3-position and a trifluoromethoxy at 5-position. In 5-(trifluoromethoxy)isatin, the carbonyl at 3-position is more reactive than the amide carbonyl at 2-position, thus it is readily functionalized under nucleophilic substitution. The nucleophilic substitution can also be enantioselective with the addition of chiral catalysts, with up to 92% ee (enantiomeric excess).

5-(Trifluoromethoxy)isatin is used to synthesize luminescent gold(I) complexes, displaying an emission at 400 nm. The isatin-gold complexes show cytotoxicity to cancer cells with half-maximal inhibitory concentration (IC50) as low as 0.28 μM. 5-(Trifluoromethoxy)isatin is also used to modify rhodamine in application of selectively detection of Cr3+. An isatin decorated fullerene (C60) has improved miscibility to P3HT in heterojunction organic solar cells.


General Information


CAS Number 169037-23-4
Chemical Formula C9H4F3NO3
Full Name 5-(Trifluoromethoxy)-1H-indole-2,3-dione
Molecular Weight 231.13 g/mol
Synonyms 5-(Trifluoromethoxy)-2,3-indolinedione
Classification / Family Fluorinated building blocks, Heterocyclic building blocks, Solar cells, OLEDs

Chemical Structure


5-(Trifluoromethoxy)isatin chemical structure, CAS 169037-23-4
5-(Trifluoromethoxy)isatin chemical structure, CAS 169037-23-4

Product Details


Purity 98%
Melting Point Tm = 170 °C – 172 °C
Appearance Orange to brown powder
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