8-Fluoro-4-hydroxy-2-methylquinoline (CAS number 5288-22-2) is consisting of a benzene-fused pyridine (quinoline) with 2-methyl, 4-hydroxyl and 8-fluoro substituents around the quinoline rings. 8-Fluoro-4-hydroxy-2-methylquinoline has multi-functional groups to allow facile reactions such as nucleophilic substitution and enamine condensation with an aldehyde. Quinoline is typically used to synthesize dyes for dye-sensitized solar cells (DSSCs) and OLEDs, due to its conjugated molecular structure. The energy gap of the molecule can be tuned effortlessly by functional group conversions.
The derivatives of quinoline are often bioactive, for instance, quinine is a well-known drug for malaria treatments. The active pharmaceutical ingredients can also be tailored into fluorescent bioimaging substances to monitor cell activities in vitro experiments.