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Bis(4-fluorophenyl)methanol

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产品名称: Bis(4-fluorophenyl)methanol
产品型号: 365-24-2
产品展商: Ossila

简单介绍


Bis(4-fluorophenyl)methanol  的详细介绍

Bis(4-fluorophenyl)methanol (CAS number 365-24-2), also referred to as 4,4'-difluorobenzhydrol, is a diphenyl methanol building block with two fluorine atoms at the para-position. Bis(4-fluorophenyl)methanol is an important building block for synthesizing antipsychotic drug such as fluspirilene, pimozide and penfluridol. Bis(4-fluorophenyl)methanol is also used in the total synthesis of Tunicamycin V, a homologous nucleoside antibiotic.

Fluspirilene chemical structure
Chemical structure of fluspirilene, an anti-psychotic drug

Bis(4-fluorophenyl)methanol is used to synthesize aromatic polyethers through nucleophilic aromatic substitution. The free hydroxy groups can be further functionalized for graft polymer with 'grafting to' method.


General Information


CAS Number 365-24-2
Chemical Formula C13H10F2O
Full Name 4,4'-Difluorobenzhydrol
Molecular Weight 220.22 g/mol
Synonyms 4,4′-Difluorobenzhydrol, Bis(4-fluorophenyl) carbinol, 4,4'-Difluorobenzhydryl alcohol
Classification / Family Fluorinated building block, APIs, Graft polymers, Functional polymers

Chemical Structure


Bis(4-fluorophenyl)methanol chemical structure
Bis(4-fluorophenyl)methanol chemical structure, CAS 365-24-2

Product Details


Purity 98%
Melting Point Tm = 43 – 45 °C
Appearance White to off-white powder

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