3,4,5-Trifluoroaniline (CAS number 163733-96-8) is an aniline building block with three fluorine atoms at 3-, 4-, and 5-positoins. 3,4,5-Trifluoroaniline is often used as an electron deficient aniline for substrate scope study in organic synthesis. Organic color centers can be produced by 3,4,5-trifluoroaniline functionalized single wall carbon nanotubes (SWCNTs), generating distinct fluorescence bands at longer wavelengths from the emission of SWCNTs (E11). The functionalization of SWCNTs is performed in one pot with 3,4,5-trifluoroaniline, SWCNTs, sodium nitrite and chlorosulfonic acid. A capsid assembly modulator that inhibits the replication of hepatitis B virus is synthesized from 3,4,5-trifluoroaniline.
A quasi-2D perovskite film consisting of lead bromide and 3,4,5-trifluoroaniline displays the maximum luminance of 1.2 × 103 cd/m2 and current efficiency up to 0.3 cd/A.