6-Chloro-8-fluoroquinoline (CAS number 52200-53-0) is a fluorinated quinoline derivative with a chlorine and a fluorine at 6- and 8-position respectively. This building block is best known for its used in active pharmaceutical ingredients (APIs), such as Besifloxacin and Clinafloxacin in topical antibiotic treatments and conjunctive bacterial infections. Other than pharmaceutical uses, 6-Chloro-8-fluoroquinoline is a synthesis intermediate for Schiff bases, through nucleophilic aromatic substitution. These Schiff bases are used for metal-ion recognition sensors because their fluorescent emissions shift after chelating to a metal center.
The Schiff bases formed by this building block are typically bidentate/tridentate ligands which readily coordinate to Ru and Ir ion centers to form dye complexes in applications of dye-sensitized solar cells(DSSCs).
Multiple functional groups
For facile synthesis
Worldwide shipping
Quick and reliable shipping
Fluorinated quinoline building block
For drug discoveries, dyes, and solar cells
High purity
>98% High purity