Bearing both bromo- and fluoro-substituents, 4-bromo-8-fluoroquinoline (CAS number 927800-38-2) is another useful intermediate for the preparation of active quinoline elements in drug discovery. Fluoroquinolines are typically used as active pharmaceutical ingredients (APIs) such as antibiotics. Additionally, 8-fluoroquinoline derivatives have also proven effective against insects, nematodes, and mites as agricultural chemicals. 4-Bromo-8-fluoroquinoline has multiple functional groups, which is an ideal candidate in substrate scopes for synthetic methodology studies.
This brominated building block can also be used as an end-capping material to extend the chromophore size of other chemicals through Pd-catalyzed cross-coupling reactions. For example, it can enhance the fluorescent signal of cyclobarbital molecularly imprinted polymer for electrochemical sensing.
Multiple functional groups
For facile synthesis
Fluorinated quinoline building block
For drug discoveries, dyes, and solar cells
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Quick and reliable shipping
High purity
>98% High purity