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3 - 氟 - 4 - 羟基苯甲醛

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产品名称: 3 - 氟 - 4 - 羟基苯甲醛
产品型号: 405-05-0
产品展商: Ossila

简单介绍


3 - 氟 - 4 - 羟基苯甲醛  的详细介绍

3-Fluoro-4-hydroxybenzaldehyde (CAS number 405-05-0) is a fluorinated benzaldehyde bearing a fluorine and a hydroxy at 3- and 4-positions. 3-Fluoro-4-hydroxybenzaldehyde is used to synthesize analogs of curcuminoid with ketones through aldol condensation. The as synthesized curcuminoid derivatives show half maximal inhibitory concentration of 0.75 μM against human ovarian cancer cell line A2780. Hydrazone derivatives can be obtained from 3-fluoro-4-hydroxybenzaldehyde with a phenylhydrazine derivatives via aldehyde-amine condensation, showing potent inhibitory of macrophage migration in anti-inflammatory activity.

3-Fluoro-4-hydroxybenzaldehyde is also exploited to synthesize caffeic acid phenylethyl amide derivatives through Wittig reaction for cytoprotective activity against peroxides.


General Information


CAS Number 405-05-0
Chemical Formula C7H5FO2
Full Name 3-Fluoro-4-hydroxybenzaldehyde
Molecular Weight 140.11 g/mol
Synonyms 2-Fluoro-4-formylphenol
Classification / Family Fluorinated building blocks, Benzaldehyde building blocks, APIs

Chemical Structure


3-Fluoro-4-hydroxybenzaldehyde chemical structure, CAS 405-05-0.
3-Fluoro-4-hydroxybenzaldehyde chemical structure, CAS 405-05-0

Product Details


Purity 97%
Melting Point Tm = 121 °C – 124 °C
Appearance Beige powder
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