产品资料
  首页 >>> 产品目录 >>> Ossila >>> 材料

2 - 氨基 - 3 - 氟吡啶

如果您对该产品感兴趣的话,可以
产品名称: 2 - 氨基 - 3 - 氟吡啶
产品型号: 21717-95-3
产品展商: Ossila

简单介绍


2 - 氨基 - 3 - 氟吡啶  的详细介绍

2-Amino-3-fluoropyridine (CAS number 21717-95-3) is derived from pyridine having an amine and a fluorine at 2- and 3-positions. 2-Amino-3-fluoropyridine can be readily introduced to molecular scaffolds by reductive amination and nucleophilic substitution. The modification by 2-amino-3-fluoropyridine has shown a significant enhancement in antitumor activity, compared with the mother molecules. It is suggested that the 2-amino-3-fluoropyridine moiety forms a π–π interaction with the arginine residue in the protein sequence, leading to improved inhibitory.

Furthermore, 2-amino-3-fluoropyridine is also used to synthesize bicyclic heterocycles such as imidazopyridines for pharmaceutical active ingredients through Baylis-Hillman reaction.


General Information


CAS Number 21717-95-3
Chemical Formula C5H5FN2
Full Name 2-Amino-3-fluoropyridine
Molecular Weight 112.11 g/mol
Synonyms 3-Fluoro-2-pyridinamine
Classification / Family Fluorinated building blocks, Heterocyclic building blocks, APIs, Bicyclic heterocycles

Chemical Structure


2-Amino-3-fluoropyridine chemical structure, CAS 21717-95-3.
2-Amino-3-fluoropyridine chemical structure, CAS 21717-95-3

Product Details


Purity 98%
Melting Point Tm = 41 °C – 45 °C
Appearance White powder/chunks
产品留言
标题
联系人
联系电话
内容
验证码
点击换一张
注:1.可以使用快捷键Alt+S或Ctrl+Enter发送信息!
2.如有必要,请您留下您的详细联系方式!