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2 - 氟 - 4 - 羟基苯甲酸

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产品名称: 2 - 氟 - 4 - 羟基苯甲酸
产品型号: 65145-13-3
产品展商: Ossila

简单介绍


2 - 氟 - 4 - 羟基苯甲酸  的详细介绍

2-Fluoro-4-hydroxybenzoic acid (CAS number 65145-13-3), a para-hydroxybenzoic acid, carries a fluoride group at ortho-position. The para-positioning of carboxylic acid and hydroxy in 2-fluoro-4-hydroxybenzoic acid is preferred for synthesizing mesogens used in liquid crystal. The long alkyl tail readily attaches to the molecule with alkyl bromide under basic condition. The ortho-positioned fluoride group introduces an additional intercalated smectic phase.

In cancer immunotherapy, an immunoadjuvant is synthesized with 2-fluoro-4-hydroxybenzoic acid and polyphosphorzene. The reaction initiates with a ring-opening polymerization of hexachlorocyclotriphosphazene, followed by a nucleophilic substitution of the deprotonated phenoxide from 2-fluoro-4-hydroxybenzoic acid.

General Information


CAS Number 65145-13-3
Chemical Formula C7H5FO3
Full Name 2-Fluoro-4-hydroxybenzoic acid
Molecular Weight 156.11 g/mol
Synonyms 4-Hydroxy-2-fluorobenzoic acid
Classification / Family Fluorinated building blocks, Benzoic acid building blocks, Liquid crystals, APIs

Chemical Structure


2-Fluoro-4-hydroxybenzoic acid chemical structure, CAS 65145-13-3.
2-Fluoro-4-hydroxybenzoic acid chemical structure, CAS 65145-13-3

Product Details


Purity 98%
Melting Point Tm = 200 °C – 202 °C
Appearance White powder
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