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2 - 氟 - 3 - 甲氧基苯甲醛

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产品名称: 2 - 氟 - 3 - 甲氧基苯甲醛
产品型号: 103438-88-6
产品展商: Ossila

简单介绍


2 - 氟 - 3 - 甲氧基苯甲醛  的详细介绍

2-Fluoro-3-methoxybenzaldehyde (CAS number 103438-88-6) is a benzaldehyde building block, bearing a fluoride and a methoxy at 2- and 3-positions. 2-Fluoro-3-methoxybenzaldehyde finds widespread use as a precursor for active pharmaceutical ingredients (APIs), particularly in the synthesis of benzosuberone derivatives. To construct benzosuberone cores, 2-fluoro-3-methoxybenzaldehyde reacts with (3-carboxypropyl)triphenylphosphonium bromide through a Wittig reaction. The formation of cycloheptanone ring is achieved through a Friedel-Craft acylation using Eaton's reagent (phosphorus pentoxide and methanesulfonic acid).

2-Fluoro-3-methoxybenzaldehyde is also employed in the synthesis of bicyclic heterocycles, including hydroisoquinolines, acrydinone and quinazolines.

General Information


CAS Number 103438-88-6
Chemical Formula C8H7FO2
Full Name 2-Fluoro-3-methoxybenzaldehyde
Molecular Weight 154.14 g/mol
Synonyms 2-Fluoro-m-anisaldehyde
Classification / Family Fluorinated building blocks, Benzaldehyde building blocks, Heterocycles, APIs

Chemical Structure


2-Fluoro-3-methoxybenzaldehyde chemical structure, CAS 103438-88-6.
2-Fluoro-3-methoxybenzaldehyde chemical structure, CAS 103438-88-6

Product Details


Purity 98%
Melting Point Tm = 47 °C – 51 °C
Appearance White crystals
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